A leader in next generation sequencing applications – the Delaware Biotechnology Institute's (DBI) DNA Sequencing & Genotyping Center -- implements the Fragment AnalyzerTM capillary electrophoresis instrument to allow researchers to accelerate their discoveries. Advanced Analytical Technologies, Inc. (AATI), an Ames, Iowa-based analytical instrumentation company, makes the Fragment AnalyzerTM.
The Academia Sinica in Taipei, Taiwan, a leader in Next Generation Sequencing, is implementing the use of the Fragment AnalyzerTM as part of their research services efforts. Advanced Analytical Technologies, Inc. (AATI), an Ames, Iowa-based analytical instrumentation company, makes the Fragment Analyzer.
There is no sign that interest in massively parallel sequencing (MPS) will fade away anytime soon. Exactly the contrary is happening: application of this technique is spreading into more and more areas of basic as well as applied research. It is getting increasingly popular among researchers investigating genomes, transcriptomes, methylomes and other nucleic acid derived –omes of many different organisms, large and small. Also the capacity of sequencing instruments is on the rise. Thanks to the possibility of pooling many barcoded libraries in one ‘lane’ it is nowadays feasible to sequence simultaneously large numbers of samples.
The Massachusetts General Hospital Center for Integrated Diagnostics in Boston has been applying molecular pathology in the ongoing battle against cancer. Patients at MGH are routinely tested with advanced, specialized clinical assays to profile their tumors at the molecular level. Identification of cancer driver mutations would enable oncologists to customize treatments for their patients in a more personalized manner or to better define the patient’s disease with respect to diagnosis and/or prognosis.