Femto Pulse

The Femto Pulse System is a novel tool for genomics and molecular biology research. Winner of a 2016 R&D 100 Award, the Femto Pulse is shattering analytic barriers for nucleic acid separation and detection.

FEMTO Pulse Awards

Femto Pulse Application Notes

Reliable gDNA QC Analysis Prior to Optical Mapping

Published:Thursday, April 19th, 2018

Optical mapping on the Saphyr from Bionano Genomics helps researchers make sense of complex genomic structures that NGS is unable to easily resolve. While powerful, the success of optical mapping on the Saphyr is dependent on the use of high-molecular weight genomic DNA that meets stringent quality standards. QC analysis of genomic DNA is complex and time-consuming. Using the Femto Pulse System, genomic DNA quality can be accurately assessed visually and with a grading scale developed to predict the performance of samples on the Saphyr.

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Quality Assessment of Genomic DNA for Biobanking Samples

Published:Thursday, April 19th, 2018

Quality assurance and quality control of nucleic acid samples are essential for biobanks and genomic handling facilities, as well as for many molecular biology applications. The revolutionary Femto Pulse System from Agilent - formerly Advanced Analytical (AATI) is the only instrument capable of replacing pulsed-field gel electrophoresis for the analysis of high molecular weight (HMW) gDNA. The Femto Pulse provides researchers with extreme sensitivity and fast separation times, with the capability of quantifying and qualifying a single cell's worth of gDNA in under 70 minutes. The FP-1002 gDNA 165 Kb Analysis Kit was designed for the separation of HMW gDNA, providing reproducible sizing, quantification, and quality control assessment with the Genomic Quality Number (GQN).

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Femto Pulse Genomic DNA Sizing and Quality Control

Published:Monday, March 19th, 2018

The revolutionary design of the Femto Pulse System from Agilent - formerly Advanced Analytical (AATI) is the only instrument capable of replacing pulsed-field gel electrophoresis analysis of high molecular weight (HMW) gDNA. The Femto Pulse has the added benefit of extreme sensitivity, with the ability to detect a single cell amount of gDNA. The FP-1002 gDNA 165 Kb Analysis Kit was designed for separation of HMW gDNA, providing accurate and reproducible sizing and quality control.

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cfDNA Separated on Femto Pulse

Published:Friday, September 22nd, 2017

Circulating cell-free DNA (cfDNA) is gaining prevalence for its potential as a non-invasive method for diagnosis and monitoring of disease. The Femto Pulse System and FP-1101 Ultra Sensitivity NGS Analysis Kit from Agilent - formerly Advanced Analytical (AATI) offer unparalleled resolution and quality assessment of low concentrated cfDNA samples separating up to seven different cfDNA fragments.

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