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Publications

Click on a subject below to go to the corresponding list of publications.

Subjects:

pKa Values log P Values Chiral Separations Oligonucleotide Purity Analysis Protein Analysis Process Monitoring Instrumentation – Capillary Electrophoresis Reviews – Capillary Electrophoresis Microbial Screening of Materials Microbial Screening of Water Enumerating Microbial Fermentations Instrumentation – Microbiology Research Applications – Microbiology

Measurement of Acid Dissociation Constants (pKa Values)

Jia, Z. "Physicochemical Profiling by Capillary Electrophoresis (Review)." Curr. Pharm. Anal. 1 (2005): 41-56.

Zhou, C., Y. Jin, J.R. Kenseth, M. Stella, K.R. Wehmeyer, and W.R. Heineman. "Rapid pKa Estimation using Vacuum-Assisted Multiplexed Capillary Electrophoresis (VAMCE) with Ultraviolet Detection." J. Pharm. Sci. 94 (2005): 576-589.

Poole, S., S. Patel, K. Dehring, H. Workman, and C.F. Poole. "Determination of Acid Dissociation Constants by Capillary Electrophoresis (Review)." J. Chromatogr. A 1037 (2004): 445-454.

Miller, J.M., A.C. Blackburn, Y. Shi, A.J. Melzak, and H.Y. Ando. "Semi-Empirical Relationships between Effective Mobility, Charge, and Molecular Weight of Pharmaceuticals by Pressure-Assisted Capillary Electrophoresis. Applications in Drug Discovery." Electrophoresis 23 (2002): 2833-2841.

Kenseth, J., A. Bastin, and D. Tallman. "A Strategy for Performing Rapid pKa Measurements on Insoluble Compounds by Multiplexed Capillary Electrophoresis." American Association of Pharmaceutical Scientists (AAPS) Annual Meeting. 2004. Poster Presentation.

Kenseth, J., K. Wong, and A. Bastin. "High Throughput Physicochemical Profiling by Multiplexed 96-Capillary Electrophoresis in Support of ADME Studies." Drug Discovery Technology (DDT) Meeting. 2005. Poster Presentation.

Measurement of Octanol-Water Partition Coefficients (log P Values)

Jia, Z. "Physicochemical Profiling by Capillary Electrophoresis (Review)." Curr. Pharm. Anal. 1 (2005): 41-56.

Wong, K.-S., J. Kenseth, and R. Strasburg. "Validation and Long-Term Assessment of an Approach for the High Throughput Determination of Lipophilicity (log P) Values Using Multiplexed, Absorbance-Based Capillary Electrophoresis." J. Pharm. Sci. 93 (2004): 916-931.

Wehmeyer, K.R., J. Tu, Y. Jin, S. King, M. Stella, D. Stanton, R. Strasburg, J. Kenseth, and K.-S. Wong. "The Application of Multiplexed Microemulsion Electrokinetic Chromatography for the Rapid Determination of log P Values for Neutral and Basic Compounds." LCGC North Am. 21 (2003): 1078-1088.

Poole, S.K., and C.F. Poole. "Separation Methods for Estimating Octanol-Water Partition Coefficients (Review)." J. Chromatogr. A 797 (2003): 3-19.

Wong, K., J. Kenseth, and D. Tallman. "High Throughput Screening of Compound Lipophilicity (log P) Values Using Multiplexed, Absorbance-Based Capillary Electrophoresis." log P 2004 Conference. 2004. Poster Presentation.

Chiral Separations

Kenseth J.R., and A. Bastin. "High-Throughput Chiral Separations Using the cePRO 9600™ Multiplexed Capillary Electrophoresis System." LCGC 22 (September 2004), S28-S29. (Advertising Supplement).

Zhong, W., and E.S. Yeung. "Combinatorial Enantiomeric Separation of Diverse Compounds Using Capillary Array Electrophoresis." Electrophoresis 23 (2002): 2996-3005.

Kenseth, J., A. Bastin, and D. Tallman. "High Throughput Enantiospecific Separations Using Multiplexed Capillary Electrophoresis with Absorbance Detection." 56th Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy. 2005. Poster Presentation.

Kenseth, J., A. Bastin, and B. Hoversten. "High Throughput Enantiospecific Separations Using Multiplexed Capillary Electrophoresis with Absorbance Detection." Chirality 2004 Meeting. 2004. Oral Presentation.

Oligonucleotide Purity Analysis

¹Wei, W., ¹Pang, H., ¹Tallman, D., ¹Kenseth, J., and ²Bogh, L.; ¹CombiSep, Inc., Ames, IA; ²Integrated DNA Technologies, Coralville, IA. "Comparisons between Multiplexed, Absorbance-based Capillary Electrophoresis, Capillary Electrophoresis, and Ion Exchange Chromatography for Analysis of n-1 Oligonucleotide Impurities." TIDES Meeting. 2005. Poster Presentation.

Protein Analysis

Luo, S., J. Feng, and H. Pang. "High-throughput Protein Analysis with the cePRO 9600™ System." Pharmaceutical Discovery 4 (October 2004), 43. (Advertising Supplement).

Luo, S., J. Feng, and H. Pang. "High-Throughput Protein Analysis by Multiplexed Sodium Dodecyl Sulfate Capillary Gel Electrophoresis with UV Absorption Detection." J. Chromatogr. A 1051 (2004): 131-134.

Luo, S., H. Pang, W. Wei, J. Kenseth, and M. McDonald. "Quantitative Analysis of Protein Aggregation Using Multiplexed Capillary Gel Electrophoresis with UV Absorption Detection." Drug Discovery Technology (DDT) Meeting. 2005. Poster Presentation.

Process Monitoring

Kittell, J., B. Borup, R. Voladari, and K. Zahn. "Parallel Capillary Electrophoresis for the Quantitative Screening of Fermentation Broths Containing Natural Products." Metab. Eng. 7 (2005): 53-58.

Zhang, Y., X. Gong, H. Zhang, R.C. Larock, and E.S. Yeung. "Combinatorial Screening of Homogeneous Catalysis and Reaction Optimization Based on Multiplexed Capillary Electrophoresis." J. Comb. Chem. 2 (2000): 450-452.

Instrumentation – Capillary Electrophoresis

Gong, X., and E.S. Yeung. "An Absorption Detection Approach for Multiplexed Capillary Electrophoresis Using a Linear Photodiode Array." Anal. Chem. 71 (1999): 4989-4996.

Reviews – Capillary Electrophoresis

Pang, H., J. Kenseth, and S. Coldiron. "High-Throughput Multiplexed Capillary Electrophoresis in Drug Discovery." Drug Discovery Today 9 (2004): 1072-1080.

Kenseth, J.R., and S.J. Coldiron. "High-Throughput Characterization and Quality Control of Small-Molecule Combinatorial Libraries." Curr. Opin. Chem. Biol. 8 (2004): 418-423.

Kenseth, J.R., Y. He, D. Tallman, H.-M. Pang, and S.J. Coldiron. "Techniques for High-Throughput Characterization of Peptides, Oligonucleotides, and Catalysis Efficiency." Curr. Opin. Chem. Biol. 8 (2004): 327-333.

Altria, K., and D. Elder. "Overview of the Status and Applications of Capillary Electrophoresis to the Analysis of Small Molecules." J. Chromatogr. A 1023 (2004): 1-14.

Microbial Screening of Materials

Steger, A.M., and J.M. Reif. "An Alternative Method for Detection of Microbial Contamination in Over-the-Counter Cough Syrups." American Society of Microbiology Annual Meeting. 2006. Poster Presentation.

¹Molitor, K.A., ¹Steger, A.M., ²Wright, D., and ²Roblin, M.; ¹Advanced Analytical Technologies, Inc., Ames, IA; ²Morinda, Inc., Orem, UT. "A Rapid Most Probable Number Test for Yeast in Nutraceutical Products." American Society of Microbiology Annual Meeting. 2006. Poster Presentation.

¹Steger, A.M., ¹Lasky, S.J., and ²Mulhall, R.C.; ¹Advanced Analytical Technologies, Inc.; ²Alberto Culver Company. "Rapid Water Monitoring and Final Product Release Utilizing a Rapid Microbiology System." IVT Microbiology Workshop, Amsterdam, The Netherlands, 2005. Oral Presentation.

Hasher-Homesley, P. Vistakon, Johnson & Johnson Vision Care, Inc. "Validation of the RBD 3000 for Bacterial Enumeration." Rapid Microbial Methods (IBC), San Diego, CA, 2004. Oral Presentation.

Microbial Screening of Water

Steger, A.M., and K.A. Harrigan. "Purified Water Monitoring Study." 7th Annual Advancing Technologies in Rapid Methods for Pharmaceutical and BioPharmaceutical Manufacturing. 2005. Oral Presentation.

Steger, A.M. "Purified Water System Monitoring and Final Product Testing Using the RBD 3000." 4th Rapid Microbiology Users' Group Conference. 2005. Oral Presentation.

Steger, A.M., and K. Harrigan. "Total Viable Organism Results of Purified Water Systems in 18 Minutes." 7th Annual Advancing Technologies in Rapid Methods, Washington, D.C., 2005. Oral Presentation.

Tangorra, P.A., C.K. Schreppel, S.J. Lasky, and A.M. Steger. "Comparison of a New Rapid Total Viable Bacteria Method vs. R2A Cultures." American Water Works Association Annual Meeting. 2004. Poster Presentation.

Reif, J.M., A.M. Steger, and S.J. Lasky. "Antibody Detection of Low-Level Contamination of Pseudomonas aeruginosa in Water Samples using the RBD Technology." American Association of Pharmaceutical Scientists Annual Meeting. 2003. Poster Presentation.

Steger, A.M., J.N. Thompson, M.D. Seager, and S.J. Lasky. "Rapid Detection of Low-Level Contamination in Purified Water Samples using RBD Technology." American Association of Pharmaceutical Scientists Annual Meeting. 2003. Poster Presentation.

Enumerating Microbial Fermentations

Reif, J.M., A.M. Steger, and K.A. Molitor. "Automated Rapid and Accurate Enumeration of Viable Microorganisms in Pure Cultures using the RBD 3000." Society for Industrial Microbiology Annual Meeting. 2006. Poster Presentation.

Reif, J.M., and A.M. Steger. "Rapid Enumeration of Biomass and Viable Mycoplasma bovis using the RBD 3000." Society for Industrial Microbiology Annual Meeting. 2005. Poster Presentation.

Fazekas-Carey, L., D.C. St. Amant, M.A. Guelta, and A.M. Steger. "Adaptation of a One-Step Automated System for Detection and Identification of Bacterial Warfare Agents." American Society of Microbiology Annual Meeting. 2004. Poster Presentation.

Lasky, S.J., and A.M. Steger. "Rapid, Specific Enumeration of Aspergillus niger Spores using the RBD Technology." Society for Industrial Microbiology Annual Meeting. 2003. Poster Presentation.

Instrumentation – Microbiology

Steger, A.M. "Advanced Analytical Technologies' RBD 3000 for Rapid Quantitative, Qualitative and Antibody-Specific Microbial Detection and Enumeration." Rapid Microbiology Newsletter. 2006 4(5).

Steger, A.M. "Rapid Enumeration of Microorganisms using Advanced Analytical's RBD 3000." Encyclopedia of Rapid Microbiological Methods, Volume 2. Ed. M. J. Miller. River Grove, IL, USA: DHI Publishing, LLC, 2005. 379-96.

Petersen, J.C. "Methods Designed to Interface with the RBD 3000 Enumeration Technology." 3C Contamination Control & Cleanroom Products, Birmingham, UK, 2005, Oral Presentation.

Hasher-Homesley, P. Vistakon, Johnson & Johnson Vision Care, Inc. "Qualification of Two RBD 3000 Systems for Bacterial Enumeration." Global Compliance Strategies for Rapid Methods in Pharmaceutical and BioPharma Manufacturing, Brussels, Belgium, 2005. Oral Presentation.

Research Applications – Microbiology

Shrestha, N.K., M.J. Tuohy, and G.W. Procop; Cleveland Clinic Foundation, Cleveland, OH. "Comparison of Flow Cytometry and Quantitative Culture for Counting Microorganisms." American Society of Microbiology Annual Meeting. 2006. Poster Presentation.

¹McNew, L.A., and ²Fazekas-Carey, L.; ¹Battelle Memorial Institute, Aberdeen, MD; ²U.S. Army, RDECOM, Aberdeen Proving Grounds, MD. "Assessment of Complex Biological Backgrounds in an Aerosol Vortex Chamber." American Society of Microbiology Annual Meeting. 2006. Poster Presentation.

¹Fazekas-Carey, L., and ²Rodriguez, C.; ¹U.S. Army, Aberdeen Proving Grounds, Edgewood, MD; ²Oak Ridge Institute for Science and Education (ORISE), Aberdeen Proving Grounds, Edgewood, MD. "Human Enteric Pathogens as Potential Terrorist Threat Agents in the Public Water Supply." American Society of Microbiology Annual Meeting. 2006. Poster Presentation.

¹Kozak, K., ²Petersen, J.C., and ²Lasky, S.J.; ¹Procter & Gamble; ²Advanced Analytical Technologies, Inc. "Rapid Microbiological Testing using Flow Cytometry in Support of Product Development," Part I (AATI), Part II (Procter & Gamble), Part III (AATI). IVT Microbiology Workshop, Amsterdam, The Netherlands. 2004. Oral Presentation.

Fazekas-Carey, L.; U.S. Army ECBC. "Adoption of a One-Step Automated System for Detection and Identification of Bacterial Warfare Agents." 7th Annual Advancing Technologies in Rapid Methods, Washington, D.C. 2005. Oral Presentation.