Literature

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Brochures

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REQUEST Micro PRO™ Microbial Detection System
REQUEST Oligo PRO™ Automated Purity Analyzer
REQUEST pKa PRO™ Measurement System
REQUEST Protein PRO™ Protein Analysis System
REQUEST AdvanCE™ FS96 Parallel Fluorescent CE System
REQUEST AdvanCE™ FS24 Parallel Fluorescent CE System
REQUEST DNA PROfiler™ Genetic Identification System

 

Application Notes and Technical Reports

Micro PRO™ Rapid Microbial Detection System

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REQUEST Screening Products for Microbial Contamination Using the Micro PRO™ Detection System
REQUEST Purified Water Monitoring Application Note
REQUEST Accurate Enumeration of Stock Cultures Using the Micro PRO™ Detection System
REQUEST Technical Report – Rapid Bacteria Counts in Microbial Adhesion Assays
REQUEST Technical Report - Rapid & Accurate Enumeration of Mycolic Acid-Containing Bacteria
REQUEST Applications for the Animal Health Industry
REQUEST Applications for the Fermentation and Probiotic Industry

 

Parallel Capillary Electrophoresis (pKa PRO™, Oligo PRO™, Protein PRO™, cePRO™)

View Title
pKa/pI Measurements
REQUEST Aqueous pKa Measurement Using the pKa PRO™
log P Measurements
REQUEST High Throughput Estimation of Octanol-Water Partition Coefficients (log Pow Values) by Multiplexed-Microemulsion Electrokinetic Chromatography with the MCE 2000(tm) System
Chiral Analysis
REQUEST High Throughput Chiral Separations using the cePRO 9600™ System
General Applications - Parallel Capillary Electrophoresis
REQUEST Performance Characteristics of the cePRO 9600™ System Part I: Migration Time and Peak Area Precision
REQUEST Multiplexed Micellar Electrokinetic Chromatography (MMEKC) Separations with the cePRO 9600™ System: Protein Tryptic Digest Analysis

 

Presentations

Micro PRO™ Rapid Microbial Detection System

View Title
Screen Finished Products and Raw Materials for Microbial Contamination
REQUEST An Alternative Method for Rapid Screening of Products for Microbial Contamination. RMUG Conference 2008.
pdf       PDF Abstract only
pdf       PDF An Alternative Method for Rapid Screening of Products for Microbial Contamination. A3P Meeting. 2008
pdf       PDF An Alternative Method for Detection of Microbial Contamination in Over-the-Counter Cough Syrups. ASM Annual Meeting 2006.
pdf       PDF A Rapid Most Probable Number Test for Yeast in Nutraceutical Products. ASM Annual Meeting 2006.
REQUEST Rapid Product Release Using the RBD 3000. SCC Annual Meeting 2006.
REQUEST Final Product Testing Using the RBD 3000 for Rapid Product Release. SCC Annual Meeting 2005.
Screen Purified/Process Water and Potable Water for Microorganisms
REQUEST Rapid TVO Results in Purified Water Systems. 7th Annual Advancing Technologies in Rapid Methods for Pharmaceutical and BioPharmaceutical Manufacturing. 2005.
pdf       PDF Abstract only
pdf       PDF Total Viable Organism Results of Purified Water Systems in 18 Minutes. AFST. 2006
pdf       PDF Comparison of a New Rapid Total Viable Bacteria Method vs. R2A Cultures. AWWA Annual Meeting 2004.
Monitor Microbial Fermentation Viability, Biomass
pdf       PDF Automated Rapid and Accurate Enumeration of Viable Microorganisms in Pure Cultures using the RBD 3000.  SIM Annual Meeting. 2006.
pdf       PDF Rapid Enumeration of Biomass and Viable Mycoplasma bovis using the RBD 3000. SIM Annual Meeting 2005.
REQUEST Adaptation of a One-Step Automated System for Detection and Identification of Bacterial Warfare Agents.  ASM Annual Meeting 2004.
Evaluate In-Process Bioburden in Egg-Based Vaccine Intermediates
pdf       PDF Application for a Rapid Flow Cytometry Method for Process Control Bioburden Testing in Live Attenuated Influenza Vaccine Intermediates.  ASM Annual Meeting 2008.
REQUEST A Rapid Method for Bio-Burden Testing in Live Attenuated Influenza Vaccine Intermediates – From Concept to Implementation.  RMUG Conference 2008.
pdf       PDF Abstract only
General Applications – Microbiology
pdf       PDF Differentiating Methicillin-Resistant and Susceptible Staphylococcus aureus by Flow Cytometry. ASM Annual Meeting 2009.
pdf       PDF The Detection of Staphylococcus aureus by Protein A Immuno-Flow Cytometry. ASM Annual Meeting 2009.
pdf       PDF Application for the Rapid Screening of Preservative Effectiveness in Liquid Pharmaceutical Products using a Flow Cytometric Method.  ASM Annual Meeting 2007.
REQUEST Real-time Detection and Identification of Militarily Significant Microorganisms. ASM Annual Meeting 2007.
REQUEST Comparison of Flow Cytometry and Quantitative Culture for Counting Microorganisms.   ASM Annual Meeting 2006.
REQUEST Assessment of Complex Biological Backgrounds in an Aerosol Vortex Chamber. ASM Annual Meeting 2006.
REQUEST Human Enteric Pathogens as Potential Terrorist Threat Agents in the Public Water Supply.   ASM Annual Meeting 2006.
REQUEST Qualification of Two RBD 3000 Systems for Bacterial Enumeration. Global Compliance Strategies for Rapid Methods in Pharmaceutical and BioPharma Manufacturing, Brussels, Belgium, 2005.
REQUEST Adoption of a One-Step Automated System for Detection and Identification of Bacterial Warfare Agents.  7th Annual Advancing Technologies in Rapid Methods, Washington, D.C. 2005.
REQUEST Validation of the RBD 3000 for Bacterial Enumeration. Rapid Microbial Methods (IBC), San Diego, CA, 2004.
REQUEST Rapid Microbiological Testing using Flow Cytometry in Support of Product Development, Part II (Procter & Gamble). IVT Microbiology Workshop, Amsterdam, The Netherlands. 2004.

 

Parallel Capillary Electrophoresis (pKa PRO™, Oligo PRO™, Protein PRO™, cePRO™)

View Title
pKa/pI Measurements
REQUEST Measurement of pKa Values, Isoelectric Point and Stability of Small Molecules and Peptides by Parallel Capillary Electrophoresis with UV Absorbance Detection.  AAPS National Meeting. 2007.
log P Measurements
REQUEST High Throughput Screening of Compound Lipophilicity (log P) Values Using Multiplexed, Absorbance-Based Capillary Electrophoresis.  log P 2004 Conference. 2004.
Chiral Separation
REQUEST High Throughput Enantiospecific Separations Using Multiplexed Capillary Electrophoresis with Absorbance Detection. 56th Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy. 2005.
pdf       PDF High Throughput Enantiospecific Separations Using Multiplexed Capillary Electrophoresis with Absorbance Detection.  Chirality 2004 Meeting. 2004.
DNA/RNA Oligonucleotide Purity Analysis
REQUEST High Throughput Characterization of Oligonucleotide and RNAi Duplex Purity by Parallel Capillary Electrophoresis.  RNAi, MicroRNAs & Oligos-2009-Boston Summit. 2009.
REQUEST Rapid Characterization of Synthetic Oligonucleotide and RNA Duplex Purity by Parallel Capillary Electrophoresis with UV Absorbance Detection. AAPS National Meeting. 2007.
pdf       PDF Comparisons between Multiplexed, Absorbance-based Capillary Electrophoresis, Capillary Electrophoresis, and Ion Exchange Chromatography for Analysis of n-1 Oligonucleotide Impurities. TIDES Meeting. 2005.
Antibody/Protein Analysis
REQUEST Protein PRO™ Technology Overview. June 2009.
dsDNA Fragment Analysis
REQUEST High Throughput dsDNA Fragment Detection and Analysis by Parallel Capillary Electrophoresis with Fluorescent Detection. Jan 2010 PAG XVIII

 

DNA PROfiler™ Genetic Identification System

View Title
Profiling for Microorganism Identification, ASM 2008
REQUEST DNA Profiling for Rapid Mycobacterium Identification with the Use Genbank Information as Reference Library. ASM 2010
REQUEST Aspergillus Identification with DNA PROfiling. ASM 2010
REQUEST Pathogenic Candida Species Identification with DNA Profiling. ASM 2009
REQUEST DNA Profiling for Characterization of Salmonella spp. ASM 2009
REQUEST The Use of the DNA PROfiler™ for the Identification of Mycobacterium species. ASM 2009
REQUEST DNA PROfiling for Detection and Characterization of Salmonella in Peanut Butter. IAFP 2010

 

PUBLICATIONS

View Title
Reviews – Rapid Microbiology Technology
LINK Rapid Microbiology – What Is Truly Possible? Am Pharm Rev. 11 (2008): 34-40. http://www.americanpharmaceuticalreview.com
LINK Advanced Analytical Technologies' RBD 3000 for Rapid Quantitative, Qualitative and Antibody-Specific Microbial Detection and Enumeration. Rapid Microbiology Newsletter. 4 (2006) 3-4 http://www.rapidmicro.org/06JanuaryFebruaryNewsletter.pdf
REQUEST Rapid Enumeration of Microorganisms using Advanced Analytical's RBD 3000. Encyclopedia of Rapid Microbiological Methods, Volume 2. Ed. M. J. Miller. River Grove, IL, USA: DHI Publishing, LLC, 2005. 379-96.
REQUEST Rapid Microbial Counting by Flow Cytometry: Validation and Implementation for Research and Development (R&D) Applications. Encyclopedia of Rapid Microbiological Methods, Volume 2. Ed. M. J. Miller. River Grove, IL, USA: DHI Publishing, LLC, 2005.
REQUEST The RBD 3000 Rapid Bacterial Enumeration System as an Alternative to Traditional Pour Plate Enumeration. Encyclopedia of Rapid Microbiological Methods, Volume 2. Ed. M. J. Miller. River Grove, IL, USA: DHI Publishing, LLC, 2005.
LINK Rapid Microbiological Methods using flow cytometry. www.americanpharmaceuticalreview.com
pKa/pI Measurements
LINK Evaluation of Multiplexed CE with UV Detection for Rapid pKa Estimation of Active Pharmaceutical Ingredients. Chromatographia, (2008): 219-225. http://www.springerlink.com
pdf       PDF Measurement of Dissociation Constants (pKa Values) of Organic Compounds by Multiplexed Capillary Electrophoresis Using Aqueous and Cosolvent Buffers. J. Pharm. Sci. 97 (2008): 2581-2606.
LINK Physicochemical Profiling by Capillary Electrophoresis (Review). Curr. Pharm. Anal. 1 (2005): 41-56. http://www.bentham.org/cpa/sample/cpa1-1.htm#52008
pdf       PDF Rapid pKa Estimation using Vacuum-Assisted Multiplexed Capillary Electrophoresis (VAMCE) with Ultraviolet Detection. J. Pharm. Sci. 94 (2005): 576-589.
LINK Determination of Acid Dissociation Constants by Capillary Electrophoresis (Review). J. Chromatogr. A 1037 (2004): 445-454. http://www.sciencedirect.com
LINK Semi-Empirical Relationships between Effective Mobility, Charge, and Molecular Weight of Pharmaceuticals by Pressure-Assisted Capillary Electrophoresis. Applications in Drug Discovery. Electrophoresis 23 (2002): 2833-2841. http://www3.interscience.wiley.com/journal/98515345/abstract
log P Measurements
LINK Physicochemical Profiling by Capillary Electrophoresis (Review). Curr. Pharm. Anal. 1 (2005): 41-56. http://www.bentham.org/cpa/sample/cpa1-1.htm#5
pdf       PDF Validation and Long-Term Assessment of an Approach for the High Throughput Determination of Lipophilicity (log P) Values Using Multiplexed, Absorbance-Based Capillary Electrophoresis. J. Pharm. Sci. 93 (2004): 916-931.
pdf       PDF The Application of Multiplexed Microemulsion Electrokinetic Chromatography for the Rapid Determination of log P Values for Neutral and Basic Compounds. LCGC North Am. 21 (2003): 1078-1088.
LINK Separation Methods for Estimating Octanol-Water Partition Coefficients (Review). J. Chromatogr. A 797 (2003): 3-19. http://www.sciencedirect.com
Chiral Analysis
pdf       PDF High-Throughput Chiral Separations Using the cePRO 9600™ Multiplexed Capillary Electrophoresis System. LCGC 22 (September 2004), S28-S29. (Advertising Supplement).
LINK Combinatorial Enantiomeric Separation of Diverse Compounds Using Capillary Array Electrophoresis. Electrophoresis 23 (2002): 2996-3005. http://www3.interscience.wiley.com/journal/98515364/abstract  
Process Monitoring
LINK Parallel Capillary Electrophoresis for the Quantitative Screening of Fermentation Broths Containing Natural Products. Metab. Eng. 7 (2005): 53-58. http://www.sciencedirect.com
REQUEST Combinatorial Screening of Homogeneous Catalysis and Reaction Optimization Based on Multiplexed Capillary Electrophoresis. J. Comb. Chem. 2 (2000): 450-452. http://pubs.acs.org/doi/abs/10.1021/cc000043b
Instrumentation – Parallel Capillary Electrophoresis
LINK An Absorption Detection Approach for Multiplexed Capillary Electrophoresis Using a Linear Photodiode Array. Anal. Chem. 71 (1999): 4989-4996. http://pubs.acs.org/doi/abs/10.1021/ac9900634
Reviews – Capillary Electrophoresis
pdf       PDF High-Throughput Multiplexed Capillary Electrophoresis in Drug Discovery. Drug Discovery Today 9 (2004): 1072-1080.
pdf       PDF High-Throughput Characterization and Quality Control of Small-Molecule Combinatorial Libraries. Curr. Opin. Chem. Biol. 8 (2004): 418-423.
REQUEST Techniques for High-Throughput Characterization of Peptides, Oligonucleotides, and Catalysis Efficiency. Curr. Opin. Chem. Biol. 8 (2004): 327-333.
REQUEST Overview of the Status and Applications of Capillary Electrophoresis to the Analysis of Small Molecules. J. Chromatogr. A 1023 (2004): 1-14.

 

Instruction Manuals for single capillary gels

View Title
Protigel
pdf       PDF Protigel™ – A sc Manual
pdf       PDF Protigel™ – P sc Manual
Oligel
pdf       PDF Oligel™ sc Manual
pdf       PDF Native Oligel™ sc Manual