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- Parallel Capillary Electrophoresis
(pKa PRO™, Oligo PRO™, Protein PRO™, cePRO™)View Title pKa/pI Measurements REQUEST Aqueous pKa Measurement Using the pKa PRO™ log P Measurements REQUEST High Throughput Estimation of Octanol-Water Partition Coefficients (log Pow Values) by Multiplexed-Microemulsion Electrokinetic Chromatography with the MCE 2000(tm) System Chiral Analysis REQUEST High Throughput Chiral Separations using the cePRO 9600™ System General Applications - Parallel Capillary Electrophoresis REQUEST Performance Characteristics of the cePRO 9600™ System Part I: Migration Time and Peak Area Precision REQUEST Multiplexed Micellar Electrokinetic Chromatography (MMEKC) Separations with the cePRO 9600™ System: Protein Tryptic Digest Analysis - Fragment Analyzer™ Automated System
- Presentations
- Parallel Capillary Electrophoresis
(pKa PRO™, Oligo PRO™, Protein PRO™, cePRO™)View Title pKa/pI Measurements REQUEST Measurement of pKa Values, Isoelectric Point and Stability of Small Molecules and Peptides by Parallel Capillary Electrophoresis with UV Absorbance Detection. AAPS National Meeting. 2007. log P Measurements REQUEST High Throughput Screening of Compound Lipophilicity (log P) Values Using Multiplexed, Absorbance-Based Capillary Electrophoresis. log P 2004 Conference. 2004. Chiral Separation REQUEST High Throughput Enantiospecific Separations Using Multiplexed Capillary Electrophoresis with Absorbance Detection. 56th Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy. 2005.
PDFHigh Throughput Enantiospecific Separations Using Multiplexed Capillary Electrophoresis with Absorbance Detection. Chirality 2004 Meeting. 2004. DNA/RNA Oligonucleotide Purity Analysis REQUEST High Throughput Characterization of Oligonucleotide and RNAi Duplex Purity by Parallel Capillary Electrophoresis. RNAi, MicroRNAs & Oligos-2009-Boston Summit. 2009. REQUEST Rapid Characterization of Synthetic Oligonucleotide and RNA Duplex Purity by Parallel Capillary Electrophoresis with UV Absorbance Detection. AAPS National Meeting. 2007.
PDFComparisons between Multiplexed, Absorbance-based Capillary Electrophoresis, Capillary Electrophoresis, and Ion Exchange Chromatography for Analysis of n-1 Oligonucleotide Impurities. TIDES Meeting. 2005. Antibody/Protein Analysis REQUEST Protein PRO™ Technology Overview. June 2009. dsDNA Fragment Analysis REQUEST High Throughput dsDNA Fragment Detection and Analysis by Parallel Capillary Electrophoresis with Fluorescent Detection. Jan 2010 PAG XVIII - DNA PROfiler™ Genetic Identification System
View Title Profiling for Microorganism Identification, ASM 2008 REQUEST DNA Profiling for Rapid Mycobacterium Identification with the Use Genbank Information as Reference Library. ASM 2010 REQUEST Aspergillus Identification with DNA PROfiling. ASM 2010 REQUEST Pathogenic Candida Species Identification with DNA Profiling. ASM 2009 REQUEST DNA Profiling for Characterization of Salmonella spp. ASM 2009 REQUEST The Use of the DNA PROfiler™ for the Identification of Mycobacterium species. ASM 2009 REQUEST DNA PROfiling for Detection and Characterization of Salmonella in Peanut Butter. IAFP 2010
- Publications
- pKa/pI Measurements
View Title LINK Evaluation of Multiplexed CE with UV Detection for Rapid pKa Estimation of Active Pharmaceutical Ingredients. Chromatographia, (2008): 219-225. http://www.springerlink.com
PDFMeasurement of Dissociation Constants (pKa Values) of Organic Compounds by Multiplexed Capillary Electrophoresis Using Aqueous and Cosolvent Buffers. J. Pharm. Sci. 97 (2008): 2581-2606. LINK Physicochemical Profiling by Capillary Electrophoresis (Review). Curr. Pharm. Anal. 1 (2005): 41-56. http://www.bentham.org/cpa/sample/cpa1-1.htm#52008
PDFRapid pKa Estimation using Vacuum-Assisted Multiplexed Capillary Electrophoresis (VAMCE) with Ultraviolet Detection. J. Pharm. Sci. 94 (2005): 576-589. LINK Determination of Acid Dissociation Constants by Capillary Electrophoresis (Review). J. Chromatogr. A 1037 (2004): 445-454. http://www.sciencedirect.com LINK Semi-Empirical Relationships between Effective Mobility, Charge, and Molecular Weight of Pharmaceuticals by Pressure-Assisted Capillary Electrophoresis. Applications in Drug Discovery. Electrophoresis 23 (2002): 2833-2841. http://www3.interscience.wiley.com/journal/98515345/abstract - log P Measurements
View Title LINK Physicochemical Profiling by Capillary Electrophoresis (Review). Curr. Pharm. Anal. 1 (2005): 41-56. http://www.bentham.org/cpa/sample/cpa1-1.htm#5
PDFValidation and Long-Term Assessment of an Approach for the High Throughput Determination of Lipophilicity (log P) Values Using Multiplexed, Absorbance-Based Capillary Electrophoresis. J. Pharm. Sci. 93 (2004): 916-931.
PDFThe Application of Multiplexed Microemulsion Electrokinetic Chromatography for the Rapid Determination of log P Values for Neutral and Basic Compounds. LCGC North Am. 21 (2003): 1078-1088. LINK Separation Methods for Estimating Octanol-Water Partition Coefficients (Review). J. Chromatogr. A 797 (2003): 3-19. http://www.sciencedirect.com - Chiral Analysis
View Title
PDFHigh-Throughput Chiral Separations Using the cePRO 9600™ Multiplexed Capillary Electrophoresis System. LCGC 22 (September 2004), S28-S29. (Advertising Supplement). LINK Combinatorial Enantiomeric Separation of Diverse Compounds Using Capillary Array Electrophoresis. Electrophoresis 23 (2002): 2996-3005. http://www3.interscience.wiley.com/journal/98515364/abstract - Process Monitoring
View Title LINK Parallel Capillary Electrophoresis for the Quantitative Screening of Fermentation Broths Containing Natural Products. Metab. Eng. 7 (2005): 53-58. http://www.sciencedirect.com REQUEST Combinatorial Screening of Homogeneous Catalysis and Reaction Optimization Based on Multiplexed Capillary Electrophoresis. J. Comb. Chem. 2 (2000): 450-452. http://pubs.acs.org/doi/abs/10.1021/cc000043b - Capillary Electrophoresis
View Title Instrumentation – Parallel Capillary Electrophoresis LINK An Absorption Detection Approach for Multiplexed Capillary Electrophoresis Using a Linear Photodiode Array. Anal. Chem. 71 (1999): 4989-4996. http://pubs.acs.org/doi/abs/10.1021/ac9900634 Reviews – Capillary Electrophoresis
PDFHigh-Throughput Multiplexed Capillary Electrophoresis in Drug Discovery. Drug Discovery Today 9 (2004): 1072-1080.
PDFHigh-Throughput Characterization and Quality Control of Small-Molecule Combinatorial Libraries. Curr. Opin. Chem. Biol. 8 (2004): 418-423. REQUEST Techniques for High-Throughput Characterization of Peptides, Oligonucleotides, and Catalysis Efficiency. Curr. Opin. Chem. Biol. 8 (2004): 327-333. REQUEST Overview of the Status and Applications of Capillary Electrophoresis to the Analysis of Small Molecules. J. Chromatogr. A 1023 (2004): 1-14.
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- Parallel Capillary Electrophoresis
