Literature

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Brochures

View	Title
REQUEST	Micro PRO™ Microbial Detection System
REQUEST	Oligo PRO™ Automated Purity Analyzer
REQUEST	pKa PRO™ Measurement System
REQUEST	Protein PRO™ Protein Analysis System
REQUEST	AdvanCE™ FS96 Parallel Fluorescent CE System
REQUEST	AdvanCE™ FS24 Parallel Fluorescent CE System
REQUEST	DNA PROfiler™ Genetic Identification System

 

Application Notes and Technical Reports

Micro PRO™ Rapid Microbial Detection System

View	Title
REQUEST	Screening Products for Microbial Contamination Using the Micro PRO™ Detection System
REQUEST	Purified Water Monitoring Application Note
REQUEST	Accurate Enumeration of Stock Cultures Using the Micro PRO™ Detection System
REQUEST	Technical Report – Rapid Bacteria Counts in Microbial Adhesion Assays
REQUEST	Technical Report - Rapid & Accurate Enumeration of Mycolic Acid-Containing Bacteria
REQUEST	Applications for the Animal Health Industry
REQUEST	Applications for the Fermentation and Probiotic Industry

 

Parallel Capillary Electrophoresis (pKa PRO™, Oligo PRO™, Protein PRO™, cePRO™)

View	Title
	pKa/pI Measurements
REQUEST	Aqueous pKa Measurement Using the pKa PRO™
	log P Measurements
REQUEST	High Throughput Estimation of Octanol-Water Partition Coefficients (log Pow Values) by Multiplexed-Microemulsion Electrokinetic Chromatography with the MCE 2000(tm) System
	Chiral Analysis
REQUEST	High Throughput Chiral Separations using the cePRO 9600™ System
	General Applications - Parallel Capillary Electrophoresis
REQUEST	Performance Characteristics of the cePRO 9600™ System Part I: Migration Time and Peak Area Precision
REQUEST	Multiplexed Micellar Electrokinetic Chromatography (MMEKC) Separations with the cePRO 9600™ System: Protein Tryptic Digest Analysis

 

Presentations

Micro PRO™ Rapid Microbial Detection System

View	Title
	Screen Finished Products and Raw Materials for Microbial Contamination
REQUEST	An Alternative Method for Rapid Screening of Products for Microbial Contamination. RMUG Conference 2008.
PDF	Abstract only
PDF	An Alternative Method for Rapid Screening of Products for Microbial Contamination. A3P Meeting. 2008
PDF	An Alternative Method for Detection of Microbial Contamination in Over-the-Counter Cough Syrups. ASM Annual Meeting 2006.
PDF	A Rapid Most Probable Number Test for Yeast in Nutraceutical Products. ASM Annual Meeting 2006.
REQUEST	Rapid Product Release Using the RBD 3000. SCC Annual Meeting 2006.
REQUEST	Final Product Testing Using the RBD 3000 for Rapid Product Release. SCC Annual Meeting 2005.
	Screen Purified/Process Water and Potable Water for Microorganisms
REQUEST	Rapid TVO Results in Purified Water Systems. 7th Annual Advancing Technologies in Rapid Methods for Pharmaceutical and BioPharmaceutical Manufacturing. 2005.
PDF	Abstract only
PDF	Total Viable Organism Results of Purified Water Systems in 18 Minutes. AFST. 2006
PDF	Comparison of a New Rapid Total Viable Bacteria Method vs. R2A Cultures. AWWA Annual Meeting 2004.
	Monitor Microbial Fermentation Viability, Biomass
PDF	Automated Rapid and Accurate Enumeration of Viable Microorganisms in Pure Cultures using the RBD 3000.  SIM Annual Meeting. 2006.
PDF	Rapid Enumeration of Biomass and Viable Mycoplasma bovis using the RBD 3000. SIM Annual Meeting 2005.
REQUEST	Adaptation of a One-Step Automated System for Detection and Identification of Bacterial Warfare Agents.  ASM Annual Meeting 2004.
	Evaluate In-Process Bioburden in Egg-Based Vaccine Intermediates
PDF	Application for a Rapid Flow Cytometry Method for Process Control Bioburden Testing in Live Attenuated Influenza Vaccine Intermediates.  ASM Annual Meeting 2008.
REQUEST	A Rapid Method for Bio-Burden Testing in Live Attenuated Influenza Vaccine Intermediates – From Concept to Implementation.  RMUG Conference 2008.
PDF	Abstract only
	General Applications – Microbiology
PDF	Differentiating Methicillin-Resistant and Susceptible Staphylococcus aureus by Flow Cytometry. ASM Annual Meeting 2009.
PDF	The Detection of Staphylococcus aureus by Protein A Immuno-Flow Cytometry. ASM Annual Meeting 2009.
PDF	Application for the Rapid Screening of Preservative Effectiveness in Liquid Pharmaceutical Products using a Flow Cytometric Method.  ASM Annual Meeting 2007.
REQUEST	Real-time Detection and Identification of Militarily Significant Microorganisms. ASM Annual Meeting 2007.
REQUEST	Comparison of Flow Cytometry and Quantitative Culture for Counting Microorganisms.   ASM Annual Meeting 2006.
REQUEST	Assessment of Complex Biological Backgrounds in an Aerosol Vortex Chamber. ASM Annual Meeting 2006.
REQUEST	Human Enteric Pathogens as Potential Terrorist Threat Agents in the Public Water Supply.   ASM Annual Meeting 2006.
REQUEST	Qualification of Two RBD 3000 Systems for Bacterial Enumeration. Global Compliance Strategies for Rapid Methods in Pharmaceutical and BioPharma Manufacturing, Brussels, Belgium, 2005.
REQUEST	Adoption of a One-Step Automated System for Detection and Identification of Bacterial Warfare Agents.  7th Annual Advancing Technologies in Rapid Methods, Washington, D.C. 2005.
REQUEST	Validation of the RBD 3000 for Bacterial Enumeration. Rapid Microbial Methods (IBC), San Diego, CA, 2004.
REQUEST	Rapid Microbiological Testing using Flow Cytometry in Support of Product Development, Part II (Procter & Gamble). IVT Microbiology Workshop, Amsterdam, The Netherlands. 2004.

 

Parallel Capillary Electrophoresis (pKa PRO™, Oligo PRO™, Protein PRO™, cePRO™)

View	Title
	pKa/pI Measurements
REQUEST	Measurement of pKa Values, Isoelectric Point and Stability of Small Molecules and Peptides by Parallel Capillary Electrophoresis with UV Absorbance Detection.  AAPS National Meeting. 2007.
	log P Measurements
REQUEST	High Throughput Screening of Compound Lipophilicity (log P) Values Using Multiplexed, Absorbance-Based Capillary Electrophoresis.  log P 2004 Conference. 2004.
	Chiral Separation
REQUEST	High Throughput Enantiospecific Separations Using Multiplexed Capillary Electrophoresis with Absorbance Detection. 56th Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy. 2005.
PDF	High Throughput Enantiospecific Separations Using Multiplexed Capillary Electrophoresis with Absorbance Detection.  Chirality 2004 Meeting. 2004.
	DNA/RNA Oligonucleotide Purity Analysis
REQUEST	High Throughput Characterization of Oligonucleotide and RNAi Duplex Purity by Parallel Capillary Electrophoresis.  RNAi, MicroRNAs & Oligos-2009-Boston Summit. 2009.
REQUEST	Rapid Characterization of Synthetic Oligonucleotide and RNA Duplex Purity by Parallel Capillary Electrophoresis with UV Absorbance Detection. AAPS National Meeting. 2007.
PDF	Comparisons between Multiplexed, Absorbance-based Capillary Electrophoresis, Capillary Electrophoresis, and Ion Exchange Chromatography for Analysis of n-1 Oligonucleotide Impurities. TIDES Meeting. 2005.
	Antibody/Protein Analysis
REQUEST	Protein PRO™ Technology Overview. June 2009.
	dsDNA Fragment Analysis
REQUEST	High Throughput dsDNA Fragment Detection and Analysis by Parallel Capillary Electrophoresis with Fluorescent Detection. Jan 2010 PAG XVIII

 

DNA PROfiler™ Genetic Identification System

View	Title
	Profiling for Microorganism Identification, ASM 2008
REQUEST	DNA Profiling for Rapid Mycobacterium Identification with the Use Genbank Information as Reference Library. ASM 2010
REQUEST	Aspergillus Identification with DNA PROfiling. ASM 2010
REQUEST	Pathogenic Candida Species Identification with DNA Profiling. ASM 2009
REQUEST	DNA Profiling for Characterization of Salmonella spp. ASM 2009
REQUEST	The Use of the DNA PROfiler™ for the Identification of Mycobacterium species. ASM 2009
REQUEST	DNA PROfiling for Detection and Characterization of Salmonella in Peanut Butter. IAFP 2010

 

PUBLICATIONS

View	Title
	Reviews – Rapid Microbiology Technology
LINK	Rapid Microbiology – What Is Truly Possible? Am Pharm Rev. 11 (2008): 34-40. http://www.americanpharmaceuticalreview.com
LINK	Advanced Analytical Technologies' RBD 3000 for Rapid Quantitative, Qualitative and Antibody-Specific Microbial Detection and Enumeration. Rapid Microbiology Newsletter. 4 (2006) 3-4 http://www.rapidmicro.org/06JanuaryFebruaryNewsletter.pdf
REQUEST	Rapid Enumeration of Microorganisms using Advanced Analytical's RBD 3000. Encyclopedia of Rapid Microbiological Methods, Volume 2. Ed. M. J. Miller. River Grove, IL, USA: DHI Publishing, LLC, 2005. 379-96.
REQUEST	Rapid Microbial Counting by Flow Cytometry: Validation and Implementation for Research and Development (R&D) Applications. Encyclopedia of Rapid Microbiological Methods, Volume 2. Ed. M. J. Miller. River Grove, IL, USA: DHI Publishing, LLC, 2005.
REQUEST	The RBD 3000 Rapid Bacterial Enumeration System as an Alternative to Traditional Pour Plate Enumeration. Encyclopedia of Rapid Microbiological Methods, Volume 2. Ed. M. J. Miller. River Grove, IL, USA: DHI Publishing, LLC, 2005.
LINK	Rapid Microbiological Methods using flow cytometry. www.americanpharmaceuticalreview.com
	pKa/pI Measurements
LINK	Evaluation of Multiplexed CE with UV Detection for Rapid pKa Estimation of Active Pharmaceutical Ingredients. Chromatographia, (2008): 219-225. http://www.springerlink.com
PDF	Measurement of Dissociation Constants (pKa Values) of Organic Compounds by Multiplexed Capillary Electrophoresis Using Aqueous and Cosolvent Buffers. J. Pharm. Sci. 97 (2008): 2581-2606.
LINK	Physicochemical Profiling by Capillary Electrophoresis (Review). Curr. Pharm. Anal. 1 (2005): 41-56. http://www.bentham.org/cpa/sample/cpa1-1.htm#52008
PDF	Rapid pKa Estimation using Vacuum-Assisted Multiplexed Capillary Electrophoresis (VAMCE) with Ultraviolet Detection. J. Pharm. Sci. 94 (2005): 576-589.
LINK	Determination of Acid Dissociation Constants by Capillary Electrophoresis (Review). J. Chromatogr. A 1037 (2004): 445-454. http://www.sciencedirect.com
LINK	Semi-Empirical Relationships between Effective Mobility, Charge, and Molecular Weight of Pharmaceuticals by Pressure-Assisted Capillary Electrophoresis. Applications in Drug Discovery. Electrophoresis 23 (2002): 2833-2841. http://www3.interscience.wiley.com/journal/98515345/abstract
	log P Measurements
LINK	Physicochemical Profiling by Capillary Electrophoresis (Review). Curr. Pharm. Anal. 1 (2005): 41-56. http://www.bentham.org/cpa/sample/cpa1-1.htm#5
PDF	Validation and Long-Term Assessment of an Approach for the High Throughput Determination of Lipophilicity (log P) Values Using Multiplexed, Absorbance-Based Capillary Electrophoresis. J. Pharm. Sci. 93 (2004): 916-931.
PDF	The Application of Multiplexed Microemulsion Electrokinetic Chromatography for the Rapid Determination of log P Values for Neutral and Basic Compounds. LCGC North Am. 21 (2003): 1078-1088.
LINK	Separation Methods for Estimating Octanol-Water Partition Coefficients (Review). J. Chromatogr. A 797 (2003): 3-19. http://www.sciencedirect.com
	Chiral Analysis
PDF	High-Throughput Chiral Separations Using the cePRO 9600™ Multiplexed Capillary Electrophoresis System. LCGC 22 (September 2004), S28-S29. (Advertising Supplement).
LINK	Combinatorial Enantiomeric Separation of Diverse Compounds Using Capillary Array Electrophoresis. Electrophoresis 23 (2002): 2996-3005. http://www3.interscience.wiley.com/journal/98515364/abstract
	Process Monitoring
LINK	Parallel Capillary Electrophoresis for the Quantitative Screening of Fermentation Broths Containing Natural Products. Metab. Eng. 7 (2005): 53-58. http://www.sciencedirect.com
REQUEST	Combinatorial Screening of Homogeneous Catalysis and Reaction Optimization Based on Multiplexed Capillary Electrophoresis. J. Comb. Chem. 2 (2000): 450-452. http://pubs.acs.org/doi/abs/10.1021/cc000043b
	Instrumentation – Parallel Capillary Electrophoresis
LINK	An Absorption Detection Approach for Multiplexed Capillary Electrophoresis Using a Linear Photodiode Array. Anal. Chem. 71 (1999): 4989-4996. http://pubs.acs.org/doi/abs/10.1021/ac9900634
	Reviews – Capillary Electrophoresis
PDF	High-Throughput Multiplexed Capillary Electrophoresis in Drug Discovery. Drug Discovery Today 9 (2004): 1072-1080.
PDF	High-Throughput Characterization and Quality Control of Small-Molecule Combinatorial Libraries. Curr. Opin. Chem. Biol. 8 (2004): 418-423.
REQUEST	Techniques for High-Throughput Characterization of Peptides, Oligonucleotides, and Catalysis Efficiency. Curr. Opin. Chem. Biol. 8 (2004): 327-333.
REQUEST	Overview of the Status and Applications of Capillary Electrophoresis to the Analysis of Small Molecules. J. Chromatogr. A 1023 (2004): 1-14.

 

Instruction Manuals for single capillary gels

View	Title
	Protigel
PDF	Protigel™ – A sc Manual
PDF	Protigel™ – P sc Manual
	Oligel
PDF	Oligel™ sc Manual
PDF	Native Oligel™ sc Manual

 

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