I want to...

Improve Separation Resolution	Improve Throughput
Increase Detection Sensitivity	Eliminate Use Of Labeled Primers
Stop Using Manual Slab Gels	Decrease Labor Prep Time
Shorten Electrophoresis Run Times	Lower Run Costs
Improve Quantity/Quality Assessment	Reduce Time to Results

I want to Improve Quantity/Quality Assessment

Analysis of microsatellite fragments both by size and quantity is not uncommon. Various methods have distinct advantages and disadvantages for quality analysis, as well as pro's and con's for quantity analysis.

SPECTROPHOTOMETERS AND FLUOROMETERS

• Only provide information about quantity.
• Lack genuine qualitative information.

SLAB GEL-BASED SYSTEMS

• Provide both assessments on quality and quantity.
• But lack the level of required accuracy, precision and sensitivity needed for many advanced molecular techniques.

REAL TIME PCR

• Provides high level of quantification accuracy
• Lacks the ability to provide qualitative results, which could be critical information.

The AdvanCE™ FS Nucleic Acids Analyzer can be used to do both. It will accurately qualify and quantify PCR amplicons. In comparison to slab gel, the AdvanCE™ FS Nucleic Acids Analyzer offers automated analysis and reduced sample handling.

And on top of everything else, because data from the instrument is recorded electronically by sensitive analytical components, researchers can use in-line analytical software to rapidly process data and provide exportable results.

The following factors allow the AdvanCE™ FS Nucleic Acids Analyzer to be used for quantity and quality analysis:

1. Ability to use a single aliquot of the sample for both quality and quantity
2. PROSize™, an intuitive analytical software package that aids in results processing
3. Fast run times (<30 minutes) and fast between run turnover times (<10 minutes)